Lipoproteins and heart disease risk
(Referred by International Fitness Therapist Neeraj Mehta)
The Monoglycerides and long chain fatty acids liberated from digested food fat must travel in the bloodstream as chylomicrons. These protein and phospholipid clusters act as emulsifiers, attracting both water and fat to enable their large lipid passengers to travel dispersed in the watery body fluids. The tissues of the body can extract whatever fat they need from chylomicrons passing by in the bloodstream. The remnants are then picked up by the liver, which dismantles them and reuses their parts.
Major lipoprotein: VLDL, LDL, HDL in addition to the chylomicrons, the body uses three other types of lipoprotein to carry fats:
•Very-low-density lipoproteins (VLDL), Which carry triglycerides and other lipids made in the liver to the body cells for their use.
•Low-density lipoprotein (LDL), transport cholesterol and other lipids to the tissues. LDL are made from VLDL after they have donated many of their triglycerides to body cells.
•High-density lipoprotein (HDL), which are critical in the process of carrying cholesterol away from body cells to the liver for disposal.
The last two of these lipoproteins, LDL and HDL, play major roles with regard to heart health and are the focus of most recommendations made for reducing the risk of heart disease.
Typical lipoprotein and demonstrates how a lipoprotein’s density changes with its lipid and protein contents.
The LDL and HDL difference The separate functions of LDL and HDL are worth a moment’s attention because they carry important implications for the health of the heart and blood vessels. Both LDL and HDL carry lipids in the blood, but LDL are larger, lighter, and richer in cholesterol ; HDL are smaller, denser, and packaged with more protein. LDL deliver triglycerides and cholesterol from the liver to the tissues; HDL scavenge excess cholesterol and phospholipids from the tissues for disposal.
Both LDL and HDL carry cholesterol, but elevated LDL concentrations in the blood are sign of high risk of heart attack, whereas elevated HDL concentrations are associated with a low risk. Thus some people refer to LDL as “bad” cholesterol and HDL as “good” cholesterol yet they carry the same kind of cholesterol. The difference to health between LDL and HDL lies in the proportions of lipids they contain and the tasks they perform, not in the type of cholesterol they carry.
(Referred by International Fitness Therapist Neeraj Mehta)
The Monoglycerides and long chain fatty acids liberated from digested food fat must travel in the bloodstream as chylomicrons. These protein and phospholipid clusters act as emulsifiers, attracting both water and fat to enable their large lipid passengers to travel dispersed in the watery body fluids. The tissues of the body can extract whatever fat they need from chylomicrons passing by in the bloodstream. The remnants are then picked up by the liver, which dismantles them and reuses their parts.
Major lipoprotein: VLDL, LDL, HDL in addition to the chylomicrons, the body uses three other types of lipoprotein to carry fats:
•Very-low-density lipoproteins (VLDL), Which carry triglycerides and other lipids made in the liver to the body cells for their use.
•Low-density lipoprotein (LDL), transport cholesterol and other lipids to the tissues. LDL are made from VLDL after they have donated many of their triglycerides to body cells.
•High-density lipoprotein (HDL), which are critical in the process of carrying cholesterol away from body cells to the liver for disposal.
The last two of these lipoproteins, LDL and HDL, play major roles with regard to heart health and are the focus of most recommendations made for reducing the risk of heart disease.
Typical lipoprotein and demonstrates how a lipoprotein’s density changes with its lipid and protein contents.
The LDL and HDL difference The separate functions of LDL and HDL are worth a moment’s attention because they carry important implications for the health of the heart and blood vessels. Both LDL and HDL carry lipids in the blood, but LDL are larger, lighter, and richer in cholesterol ; HDL are smaller, denser, and packaged with more protein. LDL deliver triglycerides and cholesterol from the liver to the tissues; HDL scavenge excess cholesterol and phospholipids from the tissues for disposal.
Both LDL and HDL carry cholesterol, but elevated LDL concentrations in the blood are sign of high risk of heart attack, whereas elevated HDL concentrations are associated with a low risk. Thus some people refer to LDL as “bad” cholesterol and HDL as “good” cholesterol yet they carry the same kind of cholesterol. The difference to health between LDL and HDL lies in the proportions of lipids they contain and the tasks they perform, not in the type of cholesterol they carry.
References/ web links:
Lipoproteins – The Real Cause of Heart Disease
www.drjosephhickey.com/?page_id=89
Lipoproteins, nutrition, and heart disease
ajcn.nutrition.org/content/75/2/191.full
Lipoproteins and Your Risk for Heart Disease - dummies
www.dummies.com/education/science/.../lipoproteins-and-your-risk-for-heart-disease/
Cardiovascular disease risk factors - Cholesterol | World Heart ...
www.world-heart-federation.org/cardiovascular.../cardiovascular-disease-risk.../choles..
Lipids, Lipoproteins, Atherosclerosis and Cardiovascular Disease - NCBI
https://www.ncbi.nlm.nih.gov › NCBI › Literature › PubMed Central (PMC)
Lipoprotein subfractions and cardiovascular disease risk. - NCBI
https://www.ncbi.nlm.nih.gov/pubmed/20531184
Lipoprotein(a), cardiovascular disease, and contemporary management.
https://www.ncbi.nlm.nih.gov/pubmed/24182706
Lipoprotein(a). What is lipoprotein(a) and why is it important?
www.docsopinion.com/health-and-nutrition/lipids/lipoprotein-a/
Lipoprotein a or Lp(a) is a risk factor for heart disease. Measurements of Lp(a) may provide additional information to traditional lipid assessment.
www.webmd.com/heart-disease/news/20090609/lipoprotein-a-linked-to-heart-attacks
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